The short answer is no.
However, there is more to that answer than meets the eye because it doesn't guarantee you will be a loser if playing at a brick-and-mortar casino or going online.
So how can there be a difference from having seemingly no chance of winning to some chance when we are still playing the same game of roulette?
It has a lot to do with how long you play and how you bet.
Let's face it, the only way you can win playing roulette is to get lucky. Sometimes we all need a little bit of luck. In fact, some people have made a fortune by wishing on a shooting star.
For example, wouldn't you rather have an ounce of luck when you have a bet to win one million than one pound?
Clearly, we can all appreciate that thought.
In ways, gambling at the casino and especially at roulette is the same. Believe it or not, I have won good money at the Grosvenor Casino in Great Yarmouth, Norfolk. This listed building has a touch of class - then I turned up!
I've won several hundred pounds betting no more than £20 - £50. And starting at small stakes is really one of the keys to winning because you set your limit and really have little to lose but something to gain.
With a little bit of help from Lady Luck.
So what's all this luck about?
As I said earlier, the only way you will win when playing fixed odds is via luck. You may imagine there is some skill involved but I don't think there is any evidence that you can manipulate the statistics to improve your chance of winning unless you cheat. I know a few of you will say you can use the martingale system and you're sure to win. The trouble is you may need a million pounds to win a tenner if black or red comes up umpteen times. And you will find that the limit of perhaps a couple of grand bet on a single number puts pay to you doubling up infinitely.
Even if you could do it, I don't think it would be a good idea. Simply because black came up 20 times, it still levels you devils it will come up again. In fact, it is slightly less as you may have noticed zero is green!
However, I do consider betting on the single number is the key to you, potentially, winning money.
To win you need a touch of luck and that can come up just as easily on a single number as it can black or red. The difference being one pays even money while the other thirty-five to one.
Simply play your stake betting on the same single number and hope it is your lucky night. If it comes up once you are pretty much guaranteed not to lose and if it comes up twice you are flying high.
It's as boring as watching paint dry, but, in my opinion, it is one of the few ways you spend a little with the chance of winning a lot.
Good luck to all.